Research in Soft and Living Matter

Faculty:                    Dr. Sharath Ananthamurthy
                                     Dr. Sarbari Bhattacharya

PhD Scholars:             Praveen P, Shruti S. Iyengar, Rekha S

 We work using optical methods to probe the structure and dynamics in soft condensed matter systems, both living and nonliving. In particular we use optical and magnetic forces to study the rheological behavior and motion of soft matter systems. Our laboratories employ tools such as optical tweezers, in various configurations, magnetic tweezers (being developed) and atomic force microscopy for measurements related to these studies. We are also interested in the problem of guidingmagnetic probes in human vasculature and are currently in the process of designing and building macro scale experiments and detectors for this.

 Recent topics of research:

  • Red blood cell optomechanics and rheology
  • Optical birefringence in cells and tissues
  • Probes for studying colloidal movement in narrow capillaries
  • Complex fluids
  • Hydrodynamic correlations between trapped fluctuators in optical tweezers
  • Raman Optical Tweezing
  • Optical trapping of semi metallic probes and detection of magnetic interactions
  • Magnetic guiding of probes in human vasculature

Recent publications:
  Journals:

1. Birefringence of a Normal Human Red Blood Cell and related Optomechanics in an Optical Trap.
    Nagesh B.V., Yogesha, Pratibha R., Praveen P., Shruthi S. Iyengar, Sarbari Bhattacharya and Sharath        Ananthamurthy
J. Biomed. Opt. 19(11) 115004-(1-12) (2014)
2. A simple model for the rotation of a trapped chiral nematic droplet under the action of a linearly polarized laser beam,

Marjan Mosallaeipour, Sharath Ananthamurthy and N.V. Madhusudana,
Euro. J. Phys.-E, (Soft Matter and Biological Physics), DOI 10.1140/epje/i2013-13093-0, (2013)
3. Rheological behavior and gelation of Tasar regenerated silk fibroin solution

Yogesha, Raghu A and Sharath Ananthamurthy,
J. Appl. Poly. Sc, DOI 10.1 002/app.40104 (2013)
4. Orientational Dynamics of Human Red Blood Cells in an Optical Trap
Praveen P., Nagesh B.V., Yogesha, Shruthi S. Iyengar, Sharath Ananthamurthy and Sarbari Bhattacharya
J. Biomed. Opt. 18(2) 025001-(1-9) (2013)
5. Optical Tweezer as a tool to characterize Antimicrobial Activity of Silver Nanoparticles.
Yogesha, Sarbari Bhattacharya, M.K. Rabinal and Sharath Ananthamurthy
Bull. Mater. Sci. 35(4) 529-532 (2012)
6. Characterizing the Rotation of Non Symmetric Objects in an Optical Tweezer
Yogesha, Sarbari Bhattacharya and Sharath Ananthamurthy
Optics Communications 285 2530-2535 (2012)

 Conference Proceedings

        1. Trapping characterization of semi metallic magnetic beads in optical tweezers

Shruthi S. Iyengar, Praveen P., Rekha S., Sharath Ananthamurthy and Sarbari Bhattacharya, Proceedings of
Photonics 2014: 12th International Conference on Fiber Optics and Photonics, IIT Kharagpur, December
13-16, 2014, T3A.40 (ISSN No: 978-1-55752-882-7)

    1. Optical properties of Red Blood Cells – An optical tweezer based analysis

Nagesh B.V., Yogesha, Pratibha R., Praveen P., Sarbari Bhattacharya and Sharath Ananthamurthy, Proc. of SPIE Vol. 8947, 89471P-1-13 (ISSN:1605-7422, ISBN: 97808194986010)

The Optical Tweezer GroupThe Optical Tweezer Group

human red blood cellA sequence of images(left to right) showing the process of orientation of a human red blood cell in an optical trap as viewed along the beam propagation direction. The images are separated temporally by 100 ms.

discussionDr.Sarbari Bhattacharya in a discussion with RekhaSelvan

lase-alignPraveen Parthasarathi aligning the laser of the dual optical trap